The particle size analyzer Anton Paar Litesizer 500 can determine the particle size, zeta potential, molecular mass, refractive index and transmittance on a wide variety of samples
The Anton Paar Litesizer 500 does all of the functions the Litesizer 100, but also measures zeta potential, molecular mass and refractive index. The unique omega-shaped cuvette for zeta potential combined with patented cmPALS technology guarantees fast, stable and reproducible zeta potential measurements, even on sensitive and turbid samples. In addition, the Litesizer 500 offers a choice of scattering angle, which gives you the optimal measurement conditions whether the sample is concentrated or dilute.
• Particle characterization from the nano- to the micrometer range.
• Particle size measurements via dynamic light scattering at three different measurement angles.
• Determination of zeta potential using patented cmPALS.
• Molecular mass and refractive index measurements.
System specifications:
Category | Particle size analyzer Litesizer 500 |
Technical specifications | |
Light source |
Semiconductor laser diode 40 mW, 658 nm |
Temperature control range | 0 °C to 90 °C |
Standard accuracy | ±0.3 °C |
Laser warm-up time | 6 min |
Dimensions (W, D, H) | 460 mm, 485 mm, 135 mm |
Weight | approx. 18 kg |
Particle size | |
Measurement principle | Dynamic Light Scattering (DLS) |
Measuring range | 0.3 nm to 10 μm (particle diameter) |
Min. sample volume | 12 µL |
Min. concentration | 0.1 mg/mL (lysozyme) |
Max. concentration | 50 %w/v (sample-dependent) |
Accuracy | Better than ±2 % on NIST traceable standards |
Repeatability | Better than ±2 % on NIST traceable standards |
Measurement angles | 15 °, 90 °, 175 ° |
Zeta potential | |
Measuring principle | Electrophoretic Light Scattering (ELS) / cmPALS |
Measuring range | >±1000 mV |
Min. sample volume | 50 µL (sample-viscosity-dependent) |
Min. sample concentration | 0.1 mg/mL (lysozyme) |
Max. sample concentration | 70 %w/v (sample-dependent) |
Accuracy | ±10 % |
Repeatability | ±3 % |
Mobility range | 10-11 m²/V.s to 2 x 10-7 m²/V.s |
Size range | 3.8 nm to 100 µm |
Max. sample conductivity | 200 mS/cm |
pH range | 2 - 12 |
Measurement angle | 15 ° |
Molecular mass | |
Measuring principle | Static Light Scattering (SLS) |
Absolute sensitivity (toluene) | >70 kcps (side-scattering) |
Measuring range (mass) | 980 Da to 20 MDa |
Measuring range (particle size) | up to 40 nm (diameter) |
Accuracy | ±10 % |
Repeatability | ±5 % |
Min. sample concentration | 0.1 mg/mL (lysozyme) |
Measurement angle | 90 ° |
Transmittance | |
Measuring range | 0 % to 100 % |
Measuring time | 10 s |
Min. sample volume | 15 µL |
Accuracy | Better than ±1 % |
Refractive index | |
Measuring range | 1.28 to 1.50 |
Min. sample volume | 1 mL |
Accuracy | ±0.5 % |
The Anton Paar Litesizer 500 does all of the functions the Litesizer 100, but also measures zeta potential, molecular mass and refractive index. The unique omega-shaped cuvette for zeta potential combined with patented cmPALS technology guarantees fast, stable and reproducible zeta potential measurements, even on sensitive and turbid samples. In addition, the Litesizer 500 offers a choice of scattering angle, which gives you the optimal measurement conditions whether the sample is concentrated or dilute.
• Particle characterization from the nano- to the micrometer range.
• Particle size measurements via dynamic light scattering at three different measurement angles.
• Determination of zeta potential using patented cmPALS.
• Molecular mass and refractive index measurements.
System specifications:
Category | Particle size analyzer Litesizer 500 |
Technical specifications | |
Light source |
Semiconductor laser diode 40 mW, 658 nm |
Temperature control range | 0 °C to 90 °C |
Standard accuracy | ±0.3 °C |
Laser warm-up time | 6 min |
Dimensions (W, D, H) | 460 mm, 485 mm, 135 mm |
Weight | approx. 18 kg |
Particle size | |
Measurement principle | Dynamic Light Scattering (DLS) |
Measuring range | 0.3 nm to 10 μm (particle diameter) |
Min. sample volume | 12 µL |
Min. concentration | 0.1 mg/mL (lysozyme) |
Max. concentration | 50 %w/v (sample-dependent) |
Accuracy | Better than ±2 % on NIST traceable standards |
Repeatability | Better than ±2 % on NIST traceable standards |
Measurement angles | 15 °, 90 °, 175 ° |
Zeta potential | |
Measuring principle | Electrophoretic Light Scattering (ELS) / cmPALS |
Measuring range | >±1000 mV |
Min. sample volume | 50 µL (sample-viscosity-dependent) |
Min. sample concentration | 0.1 mg/mL (lysozyme) |
Max. sample concentration | 70 %w/v (sample-dependent) |
Accuracy | ±10 % |
Repeatability | ±3 % |
Mobility range | 10-11 m²/V.s to 2 x 10-7 m²/V.s |
Size range | 3.8 nm to 100 µm |
Max. sample conductivity | 200 mS/cm |
pH range | 2 - 12 |
Measurement angle | 15 ° |
Molecular mass | |
Measuring principle | Static Light Scattering (SLS) |
Absolute sensitivity (toluene) | >70 kcps (side-scattering) |
Measuring range (mass) | 980 Da to 20 MDa |
Measuring range (particle size) | up to 40 nm (diameter) |
Accuracy | ±10 % |
Repeatability | ±5 % |
Min. sample concentration | 0.1 mg/mL (lysozyme) |
Measurement angle | 90 ° |
Transmittance | |
Measuring range | 0 % to 100 % |
Measuring time | 10 s |
Min. sample volume | 15 µL |
Accuracy | Better than ±1 % |
Refractive index | |
Measuring range | 1.28 to 1.50 |
Min. sample volume | 1 mL |
Accuracy | ±0.5 % |
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