• Центральный офис
  • г. Москва
  • Варшавское шоссе, д. 125 стр. 1
  • Пн-Пт с 9:00 до 18:00
Молекулярная структура
Rapamycin
CAS-номер: 53123-88-9 Заказать# RT000827 Заказать Распечатать
Описание
  • Synonyms Stereoisomer of 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3- methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14, 20, 26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1, 4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone; RAP; Sirolimus [USAN:BAN:INN]; 23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29; AY 22989; Rapamycin (TN); RPM;
  • Molecular FormulaC51H79NO13
  • Appearanceyellow solid
  • Molecular Weight914.17186
  • Density1.182 g/cm3
  • Boiling Point973.017 oC at 760 mmHg
  • Melting Point183-185 oC
  • Flash Point542.261 oC
  • Storage Temperature-20°C
  • Refractive index1.55
  • SolubilitySoluble in DMSO and Methanol
  • Biological ActivityAntifungal and immunosuppressant. Specific inhibitor of mTOR (mammalian target of Rapamycin). Complexes with FKBP-12 and binds mTOR inhibiting its activity. Inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase.
  • StabilityStable if stored as directed.
  • UsageUsed as an immunosuppressant
назад

Реаторг — это:

Комплексный подход
Оптимальное соотношение цена/качество
Собственное логистическое подразделение
Собственное производство