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Молекулярная структура
Pravastatin sodium
CAS-номер: 81131-70-6 Заказать# RT000781 Заказать Распечатать
Описание
  • Synonyms Mevalotin; Pravachol; Pravachol (TN); Pravastatine [French]; 1-Naphthaleneheptanoic acid,1,2,6,7,8,8a-hexahydro-a,?,6-trihydroxy- 2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-,monosodium salt,(aR,?R,1S,2S,6S,8S,8aR)-; Pravastatina [Spanish]; Pravastatinum [Latin]; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betas*,deltas*),2alpha,6alpha,8beta(R*),8aalpha))-; sodium (3R,5R)-7-[(1S,2R,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxy-heptanoate; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6S,8S,8aR)-; Lipostat; SQ 31000; Paravastatin;
  • Molecular FormulaC23H35NaO7
  • AppearanceWhite Crystalline Powder
  • Molecular Weight446.50957
  • Boiling Point634.5ºCat 760 mmHg
  • Melting Point154-160℃
  • Flash Point213.2 ºC
  • Storage Temperature2-8°C
  • SolubilityH2O: 19 mg/mL in water
  • Biological ActivityWater-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (K i ~ 1 nM) and displays cardioprotective properties.
  • UsagePravastatin sodium (CAS NO.81131-70-6) can be used as a competitive inhibitor of HMG-CoA reductase, Bioactive metabolite of Mevastatin
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