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Молекулярная структура
Pirfenidone
CAS-номер: 53179-13-8 Заказать# RT000756 Заказать Распечатать
Описание
  • Synonyms 5-Methyl-1-phenyl-1H-pyridin-2-one; 5-Methyl-1-phenyl-2(1H)-pyridinone; 5-Methyl-1-phenyl-2(1H)-pyridone; AMR 69; Deskar; Pirespa; Pirfenidone;
  • Molecular FormulaC12H11NO
  • AppearanceOff-White Solid
  • Molecular Weight185.22184
  • Density1.137 g/cm3
  • Boiling Point329.1ºC at 760 mmHg
  • Melting Point96-97ºC
  • Flash Point152.7 ºC
  • Storage TemperatureStore at RT
  • Refractive index1.592
  • SolubilityDMSO: ≥10 mg/mL, soluble
  • Biological ActivityAntifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation. Regulates cytokine levels following oral administration in vivo . Potent scavenger of free radicals and inhibitor of lipid p
  • Usage2(1H)-Pyridinone,5-methyl-1-phenyl- (CAS NO.53179-13-8) is used in multiple fibrotic conditions, including those of the lung, kidney and liver
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