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Молекулярная структура
Metoprolol tartrate
CAS-номер: 56392-17-7 Заказать# RT000618 Заказать Распечатать
Описание
  • Synonyms Metoprolol-(+,-) (+)-tartrate salt; 2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3- [(1-methylethyl)amino]-,(2R,3R)-2,3- dihydroxybutanedioate (2:1) (salt); Betaloc; Beloc; Seloken; Lopressor; Metoprolol tartrate (JAN/USP); Lopresor; (2R,3R)-2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol; Prestwick_1009; 2,3-dihydroxybutanedioic acid; 1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol; Lopressor (TN); Metoprolol tartaric acid;
  • EINECS260-148-9
  • Molecular Formula2(C15H25NO3).(C4H6O6)
  • Appearancewhite to off-white / powder
  • Molecular Weight684.81464
  • Boiling Point398.6 °C at 760 mmHg
  • Melting Point120 C
  • Flash Point194.9 °C
  • Storage TemperatureKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
  • SolubilityH2O: 50 mg/mL
  • Biological ActivitySelective β 1 -adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 adrenoceptors respectively). Inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo .
  • StabilityStable. Incompatible with strong oxidizing agents.
  • UsageA selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. Antihypertensive; antianginal; antiarrhythmic (class II)
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