SolubilityFreely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone.
Biological ActivitySelective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent.
UsageLosartan potassium (CAS NO.124750-99-8) can be used as a nonpeptide angiotensin II AT1-receptor antagonist.