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Молекулярная структура
Losartan Potassium
CAS-номер: 124750-99-8 Заказать# RT000581 Заказать Распечатать
Описание
  • Synonyms Lotim; L-158086; Ocsaar; Losacor; Tenopres; Lortaan; Losaprex; Hyzaar; Niten; DuP 753; Losartan monopotassium salt; MK 954; Lorzaan; Cozaar; Llosartan; Losartanpotassium; Lorzaar; 1H-Imidazole-5-methanol,2-butyl-4-chloro- 1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-,monopotassium salt; 2-Butyl-4-chloro-1-(2-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1H-imidazole-5-methanol potassium; MK-0954; Losacar; MK 0954; potassium [2-butyl-5-chloro-3-[[4-[2-(2,3,4-triaza-1-azanidacyclopenta-2,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol; Cozaar (TN);
  • Molecular FormulaC22H22ClKN6OK
  • Appearancewhite to off-white crystalline powder
  • Molecular Weight461.01
  • Boiling Point682 °C at 760mmHg
  • Melting Point183.5-184.5 deg C /Losartan/
  • Flash Point366.3 °C
  • SolubilityFreely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone.
  • Biological ActivitySelective non-peptide angiotensin AT 1 receptor antagonist. Inhibits the contractile effects of angiotensin II on rabbit aorta and jugular vein (pA 2 = 8.27). Orally active antihypertensive agent.
  • UsageLosartan potassium (CAS NO.124750-99-8) can be used as a nonpeptide angiotensin II AT1-receptor antagonist.
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