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Молекулярная структура
Colchicine
CAS-номер: 64-86-8 Заказать# RT000150 Заказать Распечатать
Описание
  • Synonyms Acetamide,N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-; Colchicine (8CI); Benzo[a]heptalene, acetamide deriv.; (-)-Colchicine; (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; Colchineos; Colchisol; Colcin; Colsaloid; Condylon; NSC 757
  • EINECS200-598-5
  • Molecular FormulaC22H25NO6
  • Appearanceyellow powder
  • Molecular Weight399.44
  • Density1.32 g/cm3
  • Boiling PointRELATIVE DENSITY
  • Melting Point150-160℃
  • Flash Point392.9°C
  • Alpha-250 o (C=1, ALCOHOL)
  • Storage TemperaturePoison room
  • Refractive index1.584
  • Biological ActivityPlant-derived alkaloid that binds to tubulin and depolymerizes microtubules.
  • StabilityStable. Light sensitive. Incompatible with strong oxidizing agents.
  • UsageAn antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal
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