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Молекулярная структура
Cisplatin
CAS-номер: 15663-27-1 Заказать# RT000130 Заказать Распечатать
Описание
  • Synonyms Neoplatin; Platosin; cis-dichlorodi-ammine platinum(ii); cis-Diammineplatinum(II) dichloride; cis-Dichlorodiamminoplatinum(II); CPDD; cisPt(II); cis-Platinum(II) diaminodichloride; Platinum(II), diamminedichloro-, cis-; Biocisplatinum; Cisplatyl; DDP (antitumor agent); Cisplatinum; azane; platinum(+2) cation; dichloride;
  • EINECS239-733-8
  • Molecular FormulaCl2H6N2Pt
  • AppearanceOrange-yellow to deep yellow solid or powder
  • Molecular Weight300.05
  • Density3.7
  • Melting Point270℃
  • Storage TemperatureStore in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked. Keep containers tightly closed. Solubility:<0.1 g/100 mL at 19 oC in water
  • Biological ActivityPotent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells
  • StabilityStable. Incompatible with oxidizing agents, aluminium, antioxidants.
  • UsageUsed as an antineoplastic
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