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Молекулярная структура
Anastrozole
CAS-номер: 120511-73-1 Заказать# RT000048 Заказать Распечатать
Описание
  • Synonyms10-Methoxy-5H-dibenz[b,f]azepine-5-carbonylchloride; 1,3-Benzenediacetonitrile,a,a,a',a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)- (9CI); 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]di(2-methylpropionitrile); 2-[3-(2-Cyano-2-propyl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropiononitrile; Asiolex; Anastrol;
  • Molecular FormulaC17H19N5
  • Appearancecrystalline solid
  • Molecular Weight293.37
  • Density1.08 g/cm3
  • Boiling Point469.7 oC at 760 mmHg
  • Melting Point81-82℃
  • Flash Point469.7 oC at 760 mmHg
  • Storage TemperatureStore in original container in a cool dark place.
  • Refractive index1.791
  • SolubilityInsoluble
  • Biological ActivityPotent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active.
  • UsageAn aromatase inhibitor. Used as an antineoplastic.
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