DESIGN AND EQUIPPING OF THE PLANT FOR SYNTHESIS OF APIs AND INTERMEDIATES

6 December 2022 News

In 2021-2022, REATORG completed a project of design and equipping a production line of cytotoxic APIs made via chemical synthesis.

First, our process engineers discussed requirements with end-users and made a list of process equipment. After the list was approved our team began design and pipping work.

Second, our design engineers needed to make a layout of the equipment in the premises provided by the customer. Our specialists have developed several variants considering many factors: the most efficient use of space, ergonomics, ease of use and maintenance of equipment, etc. As a result, an option that meets all the requirements was found.

After the layout of process equipment was approved, design engineers of REATORG completed piping work for the equipment:

•   a heat transfer fluid line for a 100L Glass Reactor;

•   a heat transfer fluid line for a glass lined reactor for 250 l and a stainless steel reactor for 100 l;

•    a cooling line for condensers of 3-x reactor units;

•    a common vacuum line for 3 reactor units;

•    a CIP line for cleaning equipment;

•    a deionized water distribution line;

•    a blow-off line for connection units with atmosphere;

•    an emergency discharge line.

In process of preparing a URS the customer adhered to the principle of maximum unification of production - the projected workshop had to contain equipment that would allow working out the maximum number of necessary technological processes.

According to these requirements, REATORG has selected the optimal list of the process equipment:

•     Glass reactor unit for 100 l (borosilicate glass 3.3)

•     Stainless steel reactor unit for 100 L

•     Glass lined reactor unit for 250L with glass auxiliary equipment

•     Temperature control machines for reactor units.

•     Chiller for the cooling line

•     Vacuum shelf dryer

Installation of equipment, process pipelines, commissioning works were carried out by the regular assembly team and the operation and service department of the REATORG company.

More photos you can find in the section "Completed Projects"

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