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Молекулярная структура
Milrinone
CAS-номер: 78415-72-2 Арт.# RT000631 Заказать Распечатать
Описание
  • Synonyms 3-CYANO-6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE; 6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE-3-CARBONITRILE; 1,6-DIHYDRO-2-METHYL-6-OXO-(3,4'-BIPYRIDINE)-5-CARBONITRILE; 1,6-DIHYDRO-2-METHYL-6-OXO-3,4-BIPYRIDINE-5-CARBONITRILe; 1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)-NICOTINONITRILE; 4’-bipyridine)-5-carbonitrile,1,6-dihydro-2-methyl-6-oxo-( win47203; Milirinone; MilrinoneUsDmf; 2-METHYL-6-OXO-1,6-DIHYDRO-3,4'-BIPYRIDINE-5-CARBONITRILE(MILRINONE); 1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)- NICOTINONITRILES(MILRINONE); 6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
  • EINECS278-903-6
  • Molecular FormulaC12H9N3O
  • AppearanceOff-white solid
  • Molecular Weight211.21936
  • Density1.28 g/cm3
  • Boiling Point448.7 °C at 760 mmHg
  • Melting Point>3000C
  • Flash Point225.2 °C
  • Storage Temperature2-8°C
  • SolubilityDMSO: >10 mg/mL
  • Biological ActivityPotent cAMP phosphodiesterase inhibitor (IC 50 = 56 nM for inhibition of PDE III). Has inotropic and vasodilator effects following oral or intravenous administration in vivo . Also available as part of the Phosphodiesterase Inhibitor Tocriset? .
  • StabilityStable. Incompatible with strong oxidizing agents.
  • UsageSelective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic
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