Doxorubicin Hcl-EINECS: 246-818-3
Molecular Formula: C27H30ClNO11
Synonyms: 5,12-Naphthacenedione,10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,hydrochloride, (8S,10S)- (9CI); 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-,hydrochloride, (8S-cis)-; Adriamycin, hydrochloride (8CI); ADM hydrochloride; ADR; Adriablastina CS; Adriacin; Adriamycin; Adriblastin; Adriblastina; Adriblastina RD; DOX HCl; FI 106; FI 6804; Lipo-Dox;
Appearance: Orange-Red Crystalline Solid
Molecular Weight: 579.99
Boiling Point: 810.3 °C at 760 mmHg
Melting Point: 216℃
Flash Point: 443.8 °C
Storage Temperature: 2-8°C
Solubility: 2% sol in water; soluble in aqueous alcohols; moderately soluble in anhydrous methanol; insoluble in non-polar organic solvents In water, 2,600 mg/L at 25 deg C (est)
Biological Activity: Antitumor antibiotic agent that inhibits DNA topoisomerase II. DNA intercalator that inhibits nucleic acid synthesis and induces apoptosis.
Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Usage: Used as an antineoplastic