Biological ActivityEndogenous agonist at histamine receptors (H 1-4 ). Released from mast cells and basophils and exhibits inflammatory, vasodilatory and bronchoconstrictory activity. Stimulates gastric acid secretion and acts as a neurotransmitter in vivo .
StabilityStable. Incompatible with strong oxidizing agents.
UsageHistamine is involved in local immune responses, regulating physiological function in the gut and as a neurotransmitter.