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Молекулярная структура
Etoposide
CAS-номер: 33419-42-0 Заказать# RT000295 Заказать Распечатать
Описание
  • Synonyms TENIPOSIDE; 4'-demethylepipodophyllotoxin-(4,6-o-(r)-ethylidene-beta-d-glucopyranoside); 4-demethylepipodophyllotoxin-beta-d-ethylideneglucoside
  • EINECS251-509-1
  • Molecular FormulaC29H32O13
  • AppearanceWhite Crystalline Powder
  • Molecular Weight588.55658
  • Density1.55 g/cm3
  • Boiling Point798.1 °C at 760 mmHg
  • Melting Point236-251℃
  • Flash Point263.6 °C
  • Storage TemperatureStore under refrigeration, in orginal container.
  • Refractive index-110.5 ° (C=0.6, CHCl3)
  • SolubilityDMSO: 30 mg/mL
  • Biological ActivityTopoisomerase II inhibitor (IC 50 = 59.2 μ M).
  • StabilityStable under normal storage and usage conditions. Avoid elevated temperatures.
  • UsageAn antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor
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